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Search Results to Stavros Manolagas

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One or more keywords matched the following items that are connected to Manolagas, Stavros

Item TypeName
Academic Article Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids.
Academic Article The skeletal effects of glucocorticoid excess override those of orchidectomy in mice.
Academic Article Dissociation of the pro-apoptotic effects of bisphosphonates on osteoclasts from their anti-apoptotic effects on osteoblasts/osteocytes with novel analogs.
Academic Article Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism.
Academic Article Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength.
Academic Article Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis.
Academic Article Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation.
Academic Article IL-6 is not required for parathyroid hormone stimulation of RANKL expression, osteoclast formation, and bone loss in mice.
Academic Article Gone with the Wnts: beta-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism.
Academic Article Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation.
Academic Article Induction of osteoblast differentiation by selective activation of kinase-mediated actions of the estrogen receptor.
Academic Article Quantifying osteoblast and osteocyte apoptosis: challenges and rewards.
Academic Article What old means to bone.
Academic Article Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts.
Academic Article Intermittent parathyroid hormone administration counteracts the adverse effects of glucocorticoids on osteoblast and osteocyte viability, bone formation, and strength in mice.
Academic Article Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo.
Academic Article Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERalpha.
Academic Article A novel locus on the X chromosome regulates post-maturity bone density changes in mice.
Academic Article For whom the bell tolls: distress signals from long-lived osteocytes and the pathogenesis of metabolic bone diseases.
Academic Article Interspecies synteny mapping identifies a quantitative trait locus for bone mineral density on human chromosome Xp22.
Academic Article The RANKL distal control region is required for the increase in RANKL expression, but not the bone loss, associated with hyperparathyroidism or lactation in adult mice.
Academic Article A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction.
Academic Article The role of estrogen and androgen receptors in bone health and disease.
Academic Article Osteoprotegerin prevents glucocorticoid-induced osteocyte apoptosis in mice.
Academic Article Increased lipid oxidation causes oxidative stress, increased peroxisome proliferator-activated receptor-gamma expression, and diminished pro-osteogenic Wnt signaling in the skeleton.
Academic Article From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis.
Academic Article Targeted deletion of a distant transcriptional enhancer of the receptor activator of nuclear factor-kappaB ligand gene reduces bone remodeling and increases bone mass.
Academic Article Receptor activator of nuclear factor ?B ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss.
Academic Article Giant osteoclast formation and long-term oral bisphosphonate therapy.
Academic Article Control of bone mass and remodeling by PTH receptor signaling in osteocytes.
Academic Article Steroids and osteoporosis: the quest for mechanisms.
Academic Article Hormones and genes of importance in bone physiology and their influence on bone mineralization and growth in Turner syndrome.
Academic Article Non-nuclear-initiated actions of the estrogen receptor protect cortical bone mass.
Academic Article Suppression of autophagy in osteocytes mimics skeletal aging.
Academic Article Matrix-embedded cells control osteoclast formation.
Academic Article FOXOs attenuate bone formation by suppressing Wnt signaling.
Academic Article Perspective: nonreproductive sites of action of reproductive hormones.
Academic Article Kinase-mediated transcription, activators of nongenotropic estrogen-like signaling (ANGELS), and osteoporosis: a different perspective on the HRT dilemma.
Academic Article Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice.
Academic Article Sex steroids and bone.
Academic Article Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids.
Academic Article Estrogen receptor-a signaling in osteoblast progenitors stimulates cortical bone accrual.
Academic Article The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone.
Academic Article Intermittent PTH stimulates periosteal bone formation by actions on post-mitotic preosteoblasts.
Academic Article Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss.
Academic Article Dysapoptosis of osteoblasts and osteocytes increases cancellous bone formation but exaggerates cortical porosity with age.
Academic Article Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation.
Academic Article Skeletal aging: from bench to bed side.
Academic Article Continuous elevation of PTH increases the number of osteoblasts via both osteoclast-dependent and -independent mechanisms.
Concept Bone Diseases
Concept Bone Development
Concept Bone Resorption
Concept Bone Diseases, Metabolic
Concept Bone Matrix
Concept Bone Marrow
Concept Bone Marrow Cells
Concept Bone Demineralization, Pathologic
Concept Bone Density
Concept Bone and Bones
Concept Bone Morphogenetic Protein 2
Concept Bone Morphogenetic Proteins
Concept Bone Remodeling
Concept Bone Density Conservation Agents
Academic Article Receptor activator of nuclear factor kappaB ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss
Academic Article Proposed standard nomenclature for new tumor necrosis factor family members involved in the regulation of bone resorption
Academic Article An Estrogen Dendrimer Conjugate Incapable of Stimulating the Nuclear-initiated Actions of Estrogen Receptors Prevents the Loss of Cortical Bone Mass in Estrogen Deficient Mice
Academic Article Lis1 Regulates Osteoclastogenesis through Small GTPase Cdc42
Academic Article Glucocorticoids Act Directly on Osteocytes to Reduce Bone Vascularity and Strength
Academic Article Apoptosis in glucorticoid-induced bone disease
Academic Article RANKL Produced by Osteocytes Contributes to the Bone Loss Induced by Hyperparathyroidism
Academic Article In: Principles of Bone Biology. John Bilezikian, Lawrence Raisz, T. John Martin, eds
Academic Article Dysapoptosis of osteoblasts and osteocytes increases cancellous bone formation but exaggerates bone porosity with age
Academic Article Suppression of Autophagy in Osteoblasts and Osteocytes Increases Oxidative Stress and Recapitulates the Effects of Aging on the Murine Skeleton
Academic Article Intermittent PTH stimulates periosteal bone formation by actions on post-miotic preosteoblasts
Academic Article Gain or Loss of FoxO Function in Osteoclasts alter Bone Mass in Mice
Academic Article Deletion of FoxO1, 3, and 4 from Osteoprogenitor Cells Increases Bone Mass throughout Life and Attenuates Adiposity in Aged Bone
Academic Article Dysfunctional Osteocytes Increase RANKL and Promote Cortical Pore Formation in Their Vicinity: a Mechanical Explanation for the Development of Cortical Porosity with Age
Academic Article Estrogen receptor-alpha signaling in osteoblast progenitors stimulates cortical bone accrual
Academic Article Commentary on "restoration of bone mass in the severly osteopenic senescant rat" Learning how to keep Homo sapiens standing tall in old age
Academic Article The ERa of Osteoblast Progenitors is Required for Normal Accrual of Cortical Bone Mass Independently of Estrogens
Academic Article The ASBMR Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism
Academic Article Targeted Expression of Catalase to Mitochondria in Cells of the Macrophage/Osteoclast Lineage Inhibits Osteoclastogenesis and Increases Bone Mass
Academic Article Estrogen loss, cytokines, macrophages, lymphocytes, osteoclasts, and bone loss: six characters in search of an author or an endocrine-immune system relay causing osteoporosis?
Academic Article Perspective: Choreography from the tomb: an emerging role of dying osteocytes in the purposeful, and perhaps not so purposeful, targeting of bone remodeling
Academic Article Cytokine production and surface antigen expression by peripheral blood mononuclear cells in postmenopausal osteoporosis (reply letter to the editor)
Academic Article FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation.
Academic Article Sirtuin1 (Sirt1) promotes cortical bone formation by preventing ?-catenin sequestration by FoxO transcription factors in osteoblast progenitors.
Academic Article Wnt signaling and osteoporosis.
Academic Article Osteocyte-derived RANKL is a critical mediator of the increased bone resorption caused by dietary calcium deficiency.
Academic Article Reproducibility of results in preclinical studies: a perspective from the bone field.
Academic Article Suppression of autophagy in osteocytes does not modify the adverse effects of glucocorticoids on cortical bone.
Academic Article The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERa Signaling in Osteoblasts and Osteoclasts.
Academic Article A. Michael Parfitt: Enlightened Scholar and Revered Mentor: May 10, 1930-May 18, 2015.
Academic Article Effects of sex steroids on bones and muscles: Similarities, parallels, and putative interactions in health and disease.
Academic Article Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs.
Academic Article Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone.
Academic Article Skeletal inflammation and attenuation of Wnt signaling, Wnt ligand expression, and bone formation in atherosclerotic ApoE-null mice.
Academic Article PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.
Academic Article Estrogens and Androgens in Skeletal Physiology and Pathophysiology.
Academic Article The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct.
Academic Article Deletion of FoxO1, 3, and 4 in Osteoblast Progenitors Attenuates the Loss of Cancellous Bone Mass in a Mouse Model of Type 1 Diabetes.
Academic Article DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age.
Academic Article Old age causes de novo intracortical bone remodeling and porosity in mice.
Academic Article The Pathophysiological Sequence of Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Male Mice.
Academic Article The Quest for Osteoporosis Mechanisms and Rational Therapies: How Far We've Come, How Much Further We Need to Go.
Academic Article Oxidation-specific epitopes restrain bone formation.
Grant OSTEOBLAST COMMITMENT AND DIFFERENTIATION BY ANGELS
Grant HORMONAL CONTROL OF CYTOKINES IN BONE AND STROMAL CELLS
Grant Molecular and Cellular Mechanisms of Osteoporosis
Grant ESTROGENS AND OSTEOCLASTOGENESIS
Grant Androgens, estrogens, and bone loss in males
Academic Article Elimination of senescent osteoclast progenitors has no effect on the age-associated loss of bone mass in mice.
Academic Article Cxcl12 Deletion in Mesenchymal Cells Increases Bone Turnover and Attenuates the Loss of Cortical Bone Caused by Estrogen Deficiency in Mice.
Academic Article Osteocalcin promotes bone mineralization but is not a hormone.
Academic Article Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors.
Academic Article A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice.
Academic Article Increased marrow adipogenesis does not contribute to age-dependent appendicular bone loss in female mice.
Academic Article Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency.
Academic Article Neutralization of oxidized phospholipids attenuates age-associated bone loss in mice.
Academic Article Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass.
Academic Article Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency.
Academic Article RETRACTED: Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass
Academic Article Retraction: Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass.
Academic Article Retraction notice to "Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass" [Bone 170(2023) 116702].

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